5th International Symposium
Nutrition, Oxygen Biology and Medicine
Development and Ageing Nutrition, Epigenetics
and Lifestyle and the Healthspan

June 5–7, 2013
Campus Des Cordeliers, Paris, France
Full Scientific Program
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Joint Meeting of the Société Française de Recherches sur les Radicaux Libres
and the Oxygen Club of California

Wednesday, June 5th


Josiane Cillard
Bertrand Friguet
Cesar Fraga
Lester Packer
Nesrin Kartal-Özer

Session I — Plant Nutrient and Healthy Aging
Andrew Waterhouse
Novel Antioxidant Reactions of Cinnamates in Wine
Fulvio Ursini
From Free Radical Scavengers to Nucleophilic Tone: A Paradigm Shift in Nutra-Ceutical Effects of Fruits and Vegetables
Valérie Schini-Kerth
Potential of Polyphenol-Rich Products to Improve Ageing-Related Impairment of the Vascular Function
Cesar Fraga
Flavanols Improving Health: Evidence and Potential Mechanisms
Gerald Rimbach
Nutrition and Healthy Ageing-Calorie Restriction or "MediterrAsian" Diet?
Balz Frei
Flavanoids: Phytochemicals, Phytonutrients, or Dietary Antioxidants?
Manfred Eggersdorfer
Micronutrient Intake in the Western World -- Status and Implications on Public Health

Thursday, June 6th

Session II — Redox Biology of Mitochondria
Michael Murphy
Targeted Bioactive and Probe Molecules to Understand Mitochondrial Redox Metabolism
Shazib Pervai
Mitochondrial Redox Metabolism in Cell Fate Signaling
Kelvin Davies
Importance of the Mitochondrial Lon Protease in Stress-Adaptation and Ageing
Bertrand Friguet
Oxidative and Glycoxidative Mitochondrial proteome Alterations During Aging and Cellular Senescence
Tilman Grune
The Lysosomal-Mitochondrial Theory of Aging Revisited

Session III — Mitochondria, Energy and Metabolic Diseases
Fawaz Haj
New Insights Into Metabolic Regulation By Protein-Tyrosine Phosphatase 1B
Tzu-Ching Meng
Recent Understanding of Hypoxia-Induced Endothelial Dysfunction in Development of Metabolic Myndromes
Zsolt Radak
Age-Associated Declines in Mitochondrial Biogenesis and Protein Quality Control Factors are Minimized By Exercise Training Via Sirtuin Activation
Christiaan Leeuwenburgh
Autophagy Induction With Life-Long and Late-Onset Interventions: Caloric Restriction Combined With Resveratrol
Li Li Ji
PGC-1α Overexpression Attenuates Mitochondrial Disorder and Inflammatory Responses in Muscle Disuse Atrophy
George A. Brooks
Modern Concepts in Mitochondrial Biogenesis and Dynamics
Junji Yodoï
Communication Between Endoplasmic Reticulum and Mitochondria by Thioredoxin
Bertrand Rihn
Nanoparticles and Mitochondrial Activity
Eduardo J. Calabrese
Hormesis: Scientific Foundations, Mechanisms and Biomedical Applications

Friday, June 7th

Session IV — Epigenetics and Nutrigenomics: Development and Aging
Steven H. Zeisel
You Are What Your Mother Ate: Nutrition and Epigenetics Influence Development
Juan Sastre
Redox Signaling and Histone Acetylation in Acute Inflammation. Relevance of Protein Phosphatase PP2A
Bharat B. Aggarwal
Getting to Know Curcumin –The Golden Spice– Through Epigenetic Changes
Michael I. Goran
Impact of Gestational and Early-Life Postnatal Factors in the Development of Obesity and Fatty Liver in Hispanic Children
Markus Schubert
Role of Insulin and Insulin-Like Growth Factor-1 Receptor Signaling for Central Proteotoxicity
Emily Ho
Inflammatory Response in Mice Is Associated with Age-Related Zinc Deficiency and Epigenetic Dysregulation of Zinc Transporters
Jose Viña
Micro RNA Regulation of Transcription Reveals Specific Patterns in Centenarians
Mario Fraga
Epigenetics and Aging: The Role of the Environment

Session V — Oral Presentations By Young Investigators
Round Table Discussion —  Epigenetics, Metabolism, and Stress


Michael Murphy
Regina Brigelius-Flohe


Steven H. Zeisel
Bharat B. Aggarwal
Eduardo Calabrese
Li Li Ji
Emily Ho
Christiaan Leeuwenburgh
Pamela E. Stark-Reed
Patricia Oteiza

Summary And Conclusions — Regina Brigelius-Flohe


Progress in Healthspan Research Award
Oxygen Club of California Young Investigator Awards
Linus Pauling Institute Award
Société Française de Recherches sur les Radicaux Libres Awards
Exon Awards (Association des Enseignants-Chercheurs de Biologie Cellulaire et Moleculaire des Facultes de Pharmacie de Langue Française)
Society for Free Radical Research–Europe Award
Oxidative Stress College Award
Faculty of Pharmacy of Rennes Award
Faculty of Sport Science of Rennes Award
2 Archives of Biochemistry and Biophysics (Elsevier) Young Investigator Awards
  Last updated: February 20, 2013    |    Comments and Questions? e-mail us at oxyclubcalifornia@ucdavis.edu